Top 70 Francis Crick Quotes (2024 Update)
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Francis Crick Quote: “It is amateurs who have one big bright beautiful idea that they can never abandon. Professionals know that they have to produce theory after theory before they are likely to hit the jackpot.”

51. “It is amateurs who have one big bright beautiful idea that they can never abandon. Professionals know that they have to produce theory after theory before they are likely to hit the jackpot.”

— Francis Crick

Francis Crick Quote: “If poly A is added to poly U, to form a double or triple helix, the combination is inactive.”

52. “If poly A is added to poly U, to form a double or triple helix, the combination is inactive.”

— Francis Crick

Francis Crick Quote: “Human beings... are far too prone to generalize from one instance. The technical word for this, interestingly enough, is superstition.”

53. “Human beings... are far too prone to generalize from one instance. The technical word for this, interestingly enough, is superstition.”

— Francis Crick

Francis Crick Quote: “A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.”

54. “A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.”

— Francis Crick

Francis Crick Quote: “Since I essentially knew nothing, I had an almost completely free choice.”

55. “Since I essentially knew nothing, I had an almost completely free choice.”

— Francis Crick

Francis Crick Quote: “Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.”

56. “Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.”

— Francis Crick

Francis Crick Quote: “If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.”

57. “If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.”

— Francis Crick

Francis Crick Quote: “A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.”

58. “A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.”

— Francis Crick

Francis Crick Quote: “The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.”

59. “The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.”

— Francis Crick

Francis Crick Quote: “Moreover the incorporation requires the same components needed for protein synthesis, and is inhibited by the same inhibitors. Thus the system is most unlikely to be a complete artefact and is very probably closely related to genuine protein synthesis.”

60. “Moreover the incorporation requires the same components needed for protein synthesis, and is inhibited by the same inhibitors. Thus the system is most unlikely to be a complete artefact and is very probably closely related to genuine protein synthesis.”

— Francis Crick

Francis Crick Quote: “It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.”

61. “It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.”

— Francis Crick

Francis Crick Quote: “It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.”

62. “It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.”

— Francis Crick

Francis Crick Quote: “If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.”

63. “If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.”

— Francis Crick

Francis Crick Quote: “Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets.”

64. “Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets.”

— Francis Crick

Francis Crick Quote: “It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.”

65. “It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.”

— Francis Crick

Francis Crick Quote: “Whatever has a beginning must have an ending.”

66. “Whatever has a beginning must have an ending.”

— Francis Crick

Francis Crick Quote: “Only gradually did I realize that this lack of qualification could be an advantage. By the time most scientists have reached age thirty they are trapped by their own expertise. They have invested so much effort in one particular field that it is often extremely difficult, at that time in their careers, to make a radical change. I, on the other hand, knew nothing, except for a basic training in somewhat old-fashioned physics and mathematics and an ability to turn my hand to new things. I.”

67. “Only gradually did I realize that this lack of qualification could be an advantage. By the time most scientists have reached age thirty they are trapped by their own expertise. They have invested so much effort in one particular field that it is often extremely difficult, at that time in their careers, to make a radical change. I, on the other hand, knew nothing, except for a basic training in somewhat old-fashioned physics and mathematics and an ability to turn my hand to new things. I.”

— Francis Crick

Francis Crick Quote: “Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.”

68. “Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.”

— Francis Crick

Francis Crick Quote: “This seems highly likely, especially as it has been shown that in several systems mutations affecting the same amino acid are extremely near together on the genetic map.”

69. “This seems highly likely, especially as it has been shown that in several systems mutations affecting the same amino acid are extremely near together on the genetic map.”

— Francis Crick

Francis Crick Quote: “The hallmark of a successful theory is that it predicts correctly facts that were not known when the theory was presented, or, better still, which were then known incorrectly. A good theory should have at least two characteristics: it should be in sharp contrast to at least one alternative idea and it should make predictions which are testable.”

70. “The hallmark of a successful theory is that it predicts correctly facts that were not known when the theory was presented, or, better still, which were then known incorrectly. A good theory should have at least two characteristics: it should be in sharp contrast to at least one alternative idea and it should make predictions which are testable.”

— Francis Crick

Francis Crick Quote: “It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.”

71. “It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.”

— Francis Crick

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