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Whereas cells in men have just a single, maternal X chromosome, cells in women have both a maternal and a paternal X chromosome. Female cells inactivate one of the two X chromosomes, resulting in a mosaic of cells with distinct combinations of gene variants. This variety could result in an immunity advantage compared to the more fixed expression in males.51.

Nicholas A. Christakis Quote: “Whereas cells in men have just a single, maternal X chromosome, cells in women have both a maternal and a paternal X chromosome. Female cells inactivate one of the two X chromosomes, resulting in a mosaic of cells with distinct combinations of gene variants. This variety could result in an immunity advantage compared to the more fixed expression in males.51.”

“Whereas cells in men have just a single, maternal X chromosome, cells in women have both a maternal and a paternal X chromosome. Female cells inactivate one of the two X chromosomes, resulting in a mosaic of cells with distinct combinations of gene variants. This variety could result in an immunity advantage compared to the more fixed expression in males.51.”

Nicholas A. Christakis

Nicholas A. Christakis Quote: “Whereas cells in men have just a single, maternal X chromosome, cells in women have both a maternal and a paternal X chromosome. Female cells inactivate one of the two X chromosomes, resulting in a mosaic of cells with distinct combinations of gene variants. This variety could result in an immunity advantage compared to the more fixed expression in males.51.”
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