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Top 20 Nadine Burke Harris Quotes (2025 Update)

Nadine Burke Harris Quote: “Twenty years of medical research has shown that childhood adversity literally gets under our skin, changing people in ways that can endure in their bodies for decades. It can tip a child’s developmental trajectory and affect physiology. It can trigger chronic inflammation and hormonal changes that can last a lifetime. It can alter the way DNA is read and how cells replicate, and it can dramatically increase the risk for heart disease, stroke, cancer, diabetes – even Alzheimer’s.”

1. “Twenty years of medical research has shown that childhood adversity literally gets under our skin, changing people in ways that can endure in their bodies for decades. It can tip a child’s developmental trajectory and affect physiology. It can trigger chronic inflammation and hormonal changes that can last a lifetime. It can alter the way DNA is read and how cells replicate, and it can dramatically increase the risk for heart disease, stroke, cancer, diabetes – even Alzheimer’s.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “These pups are not damaged goods; they are not defective. If they can get a safe, stable, and nurturing environment at an early age, the biology says that this sets them up to develop a healthy stress-response system in adulthood. As we’ve mentioned, the key to keeping a tolerable stress response from tipping over into the toxic stress zone is the presence of a buffering adult to adequately mitigate the impact of the stressor.”

2. “These pups are not damaged goods; they are not defective. If they can get a safe, stable, and nurturing environment at an early age, the biology says that this sets them up to develop a healthy stress-response system in adulthood. As we’ve mentioned, the key to keeping a tolerable stress response from tipping over into the toxic stress zone is the presence of a buffering adult to adequately mitigate the impact of the stressor.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “Sleep, mental health, healthy relationships, exercise, nutrition, and mindfulness – we saw in our patients that these six things were critical for healing. As important, the literature provided evidence of why these things were effective. Fundamentally, they all targeted the underlying biological mechanism – a dysregulated stress-response system and the neurologic, endocrine, and immune disruptions that ensued.”

3. “Sleep, mental health, healthy relationships, exercise, nutrition, and mindfulness – we saw in our patients that these six things were critical for healing. As important, the literature provided evidence of why these things were effective. Fundamentally, they all targeted the underlying biological mechanism – a dysregulated stress-response system and the neurologic, endocrine, and immune disruptions that ensued.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “Childhood adversity is a story we think we know. Children have faced trauma and stress in the form of abuse, neglect, violence, and fear since God was a boy. Parents have been getting trashed, getting arrested, and getting divorced for almost as long. The people who are smart and strong enough are able to rise above the past and triumph through the force of their own will and resilience. Or are they?”

4. “Childhood adversity is a story we think we know. Children have faced trauma and stress in the form of abuse, neglect, violence, and fear since God was a boy. Parents have been getting trashed, getting arrested, and getting divorced for almost as long. The people who are smart and strong enough are able to rise above the past and triumph through the force of their own will and resilience. Or are they?”

— Nadine Burke Harris

Nadine Burke Harris Quote: “It turns out that since 1825, researchers have known that Graves’ disease is often correlated with stressful life events, which Trinity had in spades. It was clear that her problems with emotional regulation were overlaid on the hyperthyroidism, making her time in the classroom that much more difficult. The crazy thing is that many busy physicians do their entire assessment of ADHD based on behavioral symptoms alone, without a stethoscope.”

5. “It turns out that since 1825, researchers have known that Graves’ disease is often correlated with stressful life events, which Trinity had in spades. It was clear that her problems with emotional regulation were overlaid on the hyperthyroidism, making her time in the classroom that much more difficult. The crazy thing is that many busy physicians do their entire assessment of ADHD based on behavioral symptoms alone, without a stethoscope.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “Children are compelled to give meaning to what is happening to them. When there is no clear explanation, they make one up; the intersection of trauma and the developmentally appropriate egocentrism of childhood often leads a little kid to think, I made it happen.”

6. “Children are compelled to give meaning to what is happening to them. When there is no clear explanation, they make one up; the intersection of trauma and the developmentally appropriate egocentrism of childhood often leads a little kid to think, I made it happen.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “When you put a kid who had experienced adversity in an MRI machine, you could see measurable changes to the brain structures.”

7. “When you put a kid who had experienced adversity in an MRI machine, you could see measurable changes to the brain structures.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “What I hadn’t learned was how to break the intergenerational cycle of toxic stress.”

8. “What I hadn’t learned was how to break the intergenerational cycle of toxic stress.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “This might sound simple, but I cannot overstate this: The single most important thing is recognizing what the problem is in the first place.”

9. “This might sound simple, but I cannot overstate this: The single most important thing is recognizing what the problem is in the first place.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “If we put the right protocols into place in pediatric offices across the city, country, and world, we could intervene in time to walk back epigenetic damage and change long-term health outcomes for the roughly 67 percent of the population with ACEs and their children. And, someday, their great-grandchildren.”

10. “If we put the right protocols into place in pediatric offices across the city, country, and world, we could intervene in time to walk back epigenetic damage and change long-term health outcomes for the roughly 67 percent of the population with ACEs and their children. And, someday, their great-grandchildren.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “Researchers have found that infants of depressed moms have a harder time regulating their sleep; they sleep an average of ninety-seven fewer minutes a night than infants of nondepressed moms and have more nighttime awakenings.”

11. “Researchers have found that infants of depressed moms have a harder time regulating their sleep; they sleep an average of ninety-seven fewer minutes a night than infants of nondepressed moms and have more nighttime awakenings.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “And just like two siblings with the same parents might have different eye colors, they also might have different lengths of telomeres, which can lead to different outcomes even if they experience similar doses of adversity.”

12. “And just like two siblings with the same parents might have different eye colors, they also might have different lengths of telomeres, which can lead to different outcomes even if they experience similar doses of adversity.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “Knowing that, it’s pretty obvious why this part of the brain is so critical to learning, and it’s easy to see how kids with quick-trigger amygdalae are behind the eight ball when it comes to everything from memorizing multiplication tables to spatial memory.”

13. “Knowing that, it’s pretty obvious why this part of the brain is so critical to learning, and it’s easy to see how kids with quick-trigger amygdalae are behind the eight ball when it comes to everything from memorizing multiplication tables to spatial memory.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “In the case of the rat pups, it’s the mom’s licking and grooming. In the case of a human, it could be a dad hugging and listening.”

14. “In the case of the rat pups, it’s the mom’s licking and grooming. In the case of a human, it could be a dad hugging and listening.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “The licking and grooming behavior that occurred in the pups’ first ten days of life predicted changes to their stress response that lasted for the entire lifetime. Even more startling, the changes continued into the next generation, because female pups who had high-licker moms became high lickers themselves when they had their own kids.”

15. “The licking and grooming behavior that occurred in the pups’ first ten days of life predicted changes to their stress response that lasted for the entire lifetime. Even more startling, the changes continued into the next generation, because female pups who had high-licker moms became high lickers themselves when they had their own kids.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “The licking and grooming behavior that occurred in the pups’ first ten days of life predicted changes to their stress response.”

16. “The licking and grooming behavior that occurred in the pups’ first ten days of life predicted changes to their stress response.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “In the case of a human, it could be a dad hugging and listening. The buffer is hugely important, not just to attenuate the stress hormones but also to prevent the kind of epigenetic changes that lead to a dysregulated stress response and the major health issues that come with it.”

17. “In the case of a human, it could be a dad hugging and listening. The buffer is hugely important, not just to attenuate the stress hormones but also to prevent the kind of epigenetic changes that lead to a dysregulated stress response and the major health issues that come with it.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “But to me, the most interesting part of what they found was that stress had a major impact on the length and health of telomeres, and that in turn had a major impact on the risk of disease.”

18. “But to me, the most interesting part of what they found was that stress had a major impact on the length and health of telomeres, and that in turn had a major impact on the risk of disease.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “Once again, the science is new, but it suggests that even if you start out with shorter-than-normal telomeres, you can still slow decline by increasing your telomerase with things like meditation and exercise.”

19. “Once again, the science is new, but it suggests that even if you start out with shorter-than-normal telomeres, you can still slow decline by increasing your telomerase with things like meditation and exercise.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “Apart from these revelations, the profound discovery was that our patients with four or more ACEs were twice as likely to be overweight or obese and 32.6 times as likely to have been diagnosed with learning and behavioral problems.”

20. “Apart from these revelations, the profound discovery was that our patients with four or more ACEs were twice as likely to be overweight or obese and 32.6 times as likely to have been diagnosed with learning and behavioral problems.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “As a scientist, I couldn’t accept these kinds of associations without some serious evidence.”

21. “As a scientist, I couldn’t accept these kinds of associations without some serious evidence.”

— Nadine Burke Harris

Nadine Burke Harris Quote: “Having an ACE score of two or more doubles someone’s likelihood of developing an autoimmune disease.”

22. “Having an ACE score of two or more doubles someone’s likelihood of developing an autoimmune disease.”

— Nadine Burke Harris

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